| Skandar | Persian name meaning 'bringer of good fortune'. |
| Skate | English name meaning 'to glide on ice'. |
| Skia | Greek name meaning 'shadow' or 'shade'. |
| Slaid | Scottish name meaning 'battle' or 'warrior'. |
| Slavi | Meaning glory or fame seeker. |
| Slavko | Slavic name meaning 'glory' or 'fame'. |
| Slayden | English name meaning 'valiant warrior' or 'brave fighter'. |
| Smarth | Sanskrit name meaning 'intelligent' or 'wise'. |
| Snuffleupagus | Fictional name from the children's book 'Sesame Street'. |
| Sobiestian | Man from Sebasta |
| Socrat | One who possesses wisdom |
| Soeren | Danish name meaning 'stern' or 'serious'. |
| Sofien | French name meaning 'wise' or 'intelligent'. |
| Soikka | A name meaning a small treasure. |
| Solamah | A name meaning peace and harmony. |
| Solomom | A variant meaning peace or peaceful. |
| Solomyn | A variant meaning man of peace. |
| Sondre | Norwegian name meaning 'defender of the people'. |
| Sonee | A name meaning golden or beautiful. |
| Sonic | Relating to sound or speed. |
| Sonie | A bright and golden spirit. |
| Sonnee | A variant of the name Sunny. |
| Sonnen | German name meaning 'sun' or 'sunlight'. |
| Sonney | A variant of the name Sonny. |
| Soraa | Japanese name meaning 'beautiful' or 'lovely'. |
| Sore | Feeling or showing physical pain or discomfort. |
| Sorren | Stern or strict |
| Sotiris | Greek form of Christopher, meaning 'bearing Christ'. |
| Soudrik | A person of noble character. |
| Sougand | A person with sweet fragrance. |
| Soumyadeb | A god who is gentle and peaceful. |
| Souta | Japanese name meaning 'strong and healthy'. |
| Soyal | A person who is truly unique. |
| Spade | Tool for digging or gardening, also a playing card suit. |
| Spanser | One who is a dispenser of gifts. |
| Spartacus | Roman gladiator and leader of the Thracian slaves. |
| Spearman | Person who wields a spear, often in battle or hunting. |
| Spellman | Person who practices magic or has a magical ability. |
| Spencre | A person who is a food provider. |
| Springer | Person who springs or jumps, often in sports or action. |